Review



γ secretase inhibitor compound e  (MedChemExpress)


Bioz Verified Symbol MedChemExpress is a verified supplier
Bioz Manufacturer Symbol MedChemExpress manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 94
      Buy from Supplier

    Structured Review

    MedChemExpress γ secretase inhibitor compound e
    γ Secretase Inhibitor Compound E, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 55 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/γ secretase inhibitor compound e/product/MedChemExpress
    Average 94 stars, based on 55 article reviews
    γ secretase inhibitor compound e - by Bioz Stars, 2026-02
    94/100 stars

    Images



    Similar Products

    γ secretase inhibitor compound e  (MedChemExpress)
    94
    MedChemExpress γ secretase inhibitor compound e
    γ Secretase Inhibitor Compound E, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/γ secretase inhibitor compound e/product/MedChemExpress
    Average 94 stars, based on 1 article reviews
    γ secretase inhibitor compound e - by Bioz Stars, 2026-02
    94/100 stars
    		  Buy from Supplier
    compound e gamma secretase inhibitor (gsi)  (Millipore)
    90
    Millipore compound e gamma secretase inhibitor (gsi)
    Compound E Gamma Secretase Inhibitor (Gsi), supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/compound e gamma secretase inhibitor (gsi)/product/Millipore
    Average 90 stars, based on 1 article reviews
    compound e gamma secretase inhibitor (gsi) - by Bioz Stars, 2026-02
    90/100 stars
    		  Buy from Supplier
    gamma-secretase inhibitor compound e  (Cayman Chemical)
    90
    Cayman Chemical gamma-secretase inhibitor compound e
    Gamma Secretase Inhibitor Compound E, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/gamma-secretase inhibitor compound e/product/Cayman Chemical
    Average 90 stars, based on 1 article reviews
    gamma-secretase inhibitor compound e - by Bioz Stars, 2026-02
    90/100 stars
    		  Buy from Supplier
    compound e (γ-secretase inhibitor xxi)  (Millipore)
    90
    Millipore compound e (γ-secretase inhibitor xxi)
    Compound E (γ Secretase Inhibitor Xxi), supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/compound e (γ-secretase inhibitor xxi)/product/Millipore
    Average 90 stars, based on 1 article reviews
    compound e (γ-secretase inhibitor xxi) - by Bioz Stars, 2026-02
    90/100 stars
    		  Buy from Supplier
    compound e γ secretase inhibitor cas 209986-17-4  (Millipore)
    90
    Millipore compound e γ secretase inhibitor cas 209986-17-4
    Compound E γ Secretase Inhibitor Cas 209986 17 4, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/compound e γ secretase inhibitor cas 209986-17-4/product/Millipore
    Average 90 stars, based on 1 article reviews
    compound e γ secretase inhibitor cas 209986-17-4 - by Bioz Stars, 2026-02
    90/100 stars
    		  Buy from Supplier
    compound e gamma-secretase inhibitor xxi  (Merck KGaA)
    90
    Merck KGaA compound e gamma-secretase inhibitor xxi
    Compound E Gamma Secretase Inhibitor Xxi, supplied by Merck KGaA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/compound e gamma-secretase inhibitor xxi/product/Merck KGaA
    Average 90 stars, based on 1 article reviews
    compound e gamma-secretase inhibitor xxi - by Bioz Stars, 2026-02
    90/100 stars
    		  Buy from Supplier
    γ secretase inhibitor  (MedChemExpress)
    94
    MedChemExpress γ secretase inhibitor
    γ Secretase Inhibitor, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/γ secretase inhibitor/product/MedChemExpress
    Average 94 stars, based on 1 article reviews
    γ secretase inhibitor - by Bioz Stars, 2026-02
    94/100 stars
    		  Buy from Supplier
    compound e (γ-secretase inhibitor xxi; cat. no. 565790)  (Millipore)
    90
    Millipore compound e (γ-secretase inhibitor xxi; cat. no. 565790)
    NFV inhibits the NOTCH1 pathway in a dose-dependent manner. T-ALL cells were treated with 0.1% D, NFV or 1 μ M CE for 16 h. Immunoblotting analyses were performed. CE was used as a control to confirm NOTCH1 inhibition. T-ALL, T cell acute lymphoblastic leukemia; NICD, NOTCH1 intracellular domain; HES1, hairy and enhancer of split-1; NFV, nelfinavir; D, DMSO; CE, compound E.
    Compound E (γ Secretase Inhibitor Xxi; Cat. No. 565790), supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/compound e (γ-secretase inhibitor xxi; cat. no. 565790)/product/Millipore
    Average 90 stars, based on 1 article reviews
    compound e (γ-secretase inhibitor xxi; cat. no. 565790) - by Bioz Stars, 2026-02
    90/100 stars
    		  Buy from Supplier
    γ secretase inhibitor xxi  (Santa Cruz Biotechnology)
    93
    Santa Cruz Biotechnology γ secretase inhibitor xxi
    NFV inhibits the NOTCH1 pathway in a dose-dependent manner. T-ALL cells were treated with 0.1% D, NFV or 1 μ M CE for 16 h. Immunoblotting analyses were performed. CE was used as a control to confirm NOTCH1 inhibition. T-ALL, T cell acute lymphoblastic leukemia; NICD, NOTCH1 intracellular domain; HES1, hairy and enhancer of split-1; NFV, nelfinavir; D, DMSO; CE, compound E.
    γ Secretase Inhibitor Xxi, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/γ secretase inhibitor xxi/product/Santa Cruz Biotechnology
    Average 93 stars, based on 1 article reviews
    γ secretase inhibitor xxi - by Bioz Stars, 2026-02
    93/100 stars
    		  Buy from Supplier

    Image Search Results


    NFV inhibits the NOTCH1 pathway in a dose-dependent manner. T-ALL cells were treated with 0.1% D, NFV or 1 μ M CE for 16 h. Immunoblotting analyses were performed. CE was used as a control to confirm NOTCH1 inhibition. T-ALL, T cell acute lymphoblastic leukemia; NICD, NOTCH1 intracellular domain; HES1, hairy and enhancer of split-1; NFV, nelfinavir; D, DMSO; CE, compound E.

    Journal: International Journal of Oncology

    Article Title: Inhibition of the NOTCH and mTOR pathways by nelfinavir as a novel treatment for T cell acute lymphoblastic leukemia

    doi: 10.3892/ijo.2023.5576

    Figure Lengend Snippet: NFV inhibits the NOTCH1 pathway in a dose-dependent manner. T-ALL cells were treated with 0.1% D, NFV or 1 μ M CE for 16 h. Immunoblotting analyses were performed. CE was used as a control to confirm NOTCH1 inhibition. T-ALL, T cell acute lymphoblastic leukemia; NICD, NOTCH1 intracellular domain; HES1, hairy and enhancer of split-1; NFV, nelfinavir; D, DMSO; CE, compound E.

    Article Snippet: Compound E (γ-secretase inhibitor XXI; cat. no. 565790) and a fluorogenic γ-secretase substrate (cat. no. 565764) were purchased from Sigma-Aldrich (Merck KGaA).

    Techniques: Western Blot, Inhibition

    NFV inhibits γ-secretase activity in T-ALL cell lines. NFV decreased relative fluorescence in cell-free in vitro γ-secretase assay in a dose-dependent manner using cell membrane-enriched fractions. CE was used as a control to confirm specificity of fluorogenic substrate cleavage by endogenous γ-secretase. Data are the mean ± SD of at least three separate experiments. * P<0.05, ** P<0.01. T-ALL, T cell acute lymphoblastic leukemia; NFV, nelfinavir; D, DMSO; CE, compound E.

    Journal: International Journal of Oncology

    Article Title: Inhibition of the NOTCH and mTOR pathways by nelfinavir as a novel treatment for T cell acute lymphoblastic leukemia

    doi: 10.3892/ijo.2023.5576

    Figure Lengend Snippet: NFV inhibits γ-secretase activity in T-ALL cell lines. NFV decreased relative fluorescence in cell-free in vitro γ-secretase assay in a dose-dependent manner using cell membrane-enriched fractions. CE was used as a control to confirm specificity of fluorogenic substrate cleavage by endogenous γ-secretase. Data are the mean ± SD of at least three separate experiments. * P<0.05, ** P<0.01. T-ALL, T cell acute lymphoblastic leukemia; NFV, nelfinavir; D, DMSO; CE, compound E.

    Article Snippet: Compound E (γ-secretase inhibitor XXI; cat. no. 565790) and a fluorogenic γ-secretase substrate (cat. no. 565764) were purchased from Sigma-Aldrich (Merck KGaA).

    Techniques: Activity Assay, Fluorescence, In Vitro, Membrane

    NFV blocks presenilin 1 processing. T-ALL cells were treated with 0.1% D, 20 μ M NFV or 1 μ M CE for 16 h. FL and CTF presenilin 1 levels were assessed using immunoblotting analysis. T-ALL, T cell acute lymphoblastic leukemia; NFV, nelfinavir; D, DMSO; CE, compound E; FL, full-length; CTF, C-terminal fragment.

    Journal: International Journal of Oncology

    Article Title: Inhibition of the NOTCH and mTOR pathways by nelfinavir as a novel treatment for T cell acute lymphoblastic leukemia

    doi: 10.3892/ijo.2023.5576

    Figure Lengend Snippet: NFV blocks presenilin 1 processing. T-ALL cells were treated with 0.1% D, 20 μ M NFV or 1 μ M CE for 16 h. FL and CTF presenilin 1 levels were assessed using immunoblotting analysis. T-ALL, T cell acute lymphoblastic leukemia; NFV, nelfinavir; D, DMSO; CE, compound E; FL, full-length; CTF, C-terminal fragment.

    Article Snippet: Compound E (γ-secretase inhibitor XXI; cat. no. 565790) and a fluorogenic γ-secretase substrate (cat. no. 565764) were purchased from Sigma-Aldrich (Merck KGaA).

    Techniques: Western Blot